Silica and Connective Tissue Disorders: The Important Role of the Dermatologist

Dermatological manifestations of connective tissue diseases (CTDs) are common and frequently precede other symptoms. Thus, dermatologists may be the first clinicians to diagnose these disorders. Silica exposure is an acknowledged cause several CTDs, but this under-appreciated by clinicians, who also unaware wide range jobs in which silica can occur. The CTDs associated with include systemic sclerosis (SSc), rheumatoid arthritis (RA), lupus erythematosus (SLE), anti-neutrophil cytoplasmic antibody (ANCA) positive vasculitis overlap syndromes. Silica-related (Si-SSc) a specific profile more severe disease. Silicosis has re-emerged worldwide recently due new workplace exposures, including type silicosis (artificial stone (AS) silicosis), particularly high rate auto-antibody formation. Dangerous work practices still occurring. This article summarises recent literature on topic resurgence silica-induced reminds importance taking thorough occupational history all patients. Early intervention reduction dust reduce risk improve prognosis. Treatment options rapidly improving.